Viagra (sildenafil citrate)

Viagra (sildenafil citrate)

$ 0.76 per pill

Quick Overview

Generic Viagra is the first and the most well-known remedy for male erection. Its active ingredient is called Sildenafil. It provides enhanced blood flow to male genital area. The cavernous body are relaxed, then are filled with blood abundantly, whereby an erection appears, sufficient to perform an act of intimacy. Sildenafil has no effect on the brain. An erection is achieved only if there is a natural sexual arousal.

Manufacturer: Aurochem Pharmaceutical Pvt. Ltd., Centurion Laboratories, Fortune Healthcare Pvt Ltd, Fortune Healthcare Pvt Ltd.

Viagra: Sildenafil (Aurochem Pharmaceutical Pvt. Ltd.) , Cenforce (Centurion Laboratories) , Fildena (Fortune Healthcare Pvt Ltd) , Filagra (Fortune Healthcare Pvt Ltd.)

Viagra (Sildenafil citrate) 200 mg

Viagra
Sildenafil citrate
200 mg x 180 pills
$ 473.90 $ 450.95
$ 2.51 per pill
Buy
Viagra
Sildenafil citrate
200 mg x 120 pills
$ 357.90 $ 339.95
$ 2.83 per pill
Buy
Viagra
Sildenafil citrate
200 mg x 90 pills
$ 295.90 $ 280.95
$ 3.12 per pill
Buy
Viagra
Sildenafil citrate
200 mg x 60 pills
$ 224.90 $ 212.95
$ 3.55 per pill
Buy
Viagra
Sildenafil citrate
200 mg x 30 pills
$ 134.90 $ 127.95
$ 4.26 per pill
Buy
Viagra
Sildenafil citrate
200 mg x 20 pills
$ 99.90 $ 93.95
$ 4.70 per pill
Buy
Viagra
Sildenafil citrate
200 mg x 10 pills
$ 55.90 $ 51.95
$ 5.20 per pill
Buy

Viagra (Sildenafil citrate) 150 mg

Viagra
Sildenafil citrate
150 mg x 360 pills
$ 612.90 $ 582.95
$ 1.62 per pill
Buy
Viagra
Sildenafil citrate
150 mg x 270 pills
$ 540.90 $ 513.95
$ 1.90 per pill
Buy
Viagra
Sildenafil citrate
150 mg x 180 pills
$ 408.90 $ 388.95
$ 2.16 per pill
Buy
Viagra
Sildenafil citrate
150 mg x 120 pills
$ 307.90 $ 291.95
$ 2.43 per pill
Buy
Viagra
Sildenafil citrate
150 mg x 90 pills
$ 255.90 $ 242.95
$ 2.70 per pill
Buy
Viagra
Sildenafil citrate
150 mg x 60 pills
$ 190.90 $ 180.95
$ 3.02 per pill
Buy
Viagra
Sildenafil citrate
150 mg x 30 pills
$ 103.90 $ 97.95
$ 3.27 per pill
Buy
Viagra
Sildenafil citrate
150 mg x 20 pills
$ 77.90 $ 72.95
$ 3.65 per pill
Buy
Viagra
Sildenafil citrate
150 mg x 10 pills
$ 44.90 $ 41.95
$ 4.20 per pill
Buy

Viagra (Sildenafil citrate) 130 mg

Viagra
Sildenafil citrate
130 mg x 180 pills
$ 368.90 $ 350.95
$ 1.95 per pill
Buy
Viagra
Sildenafil citrate
130 mg x 120 pills
$ 287.90 $ 272.95
$ 2.27 per pill
Buy
Viagra
Sildenafil citrate
130 mg x 90 pills
$ 233.90 $ 221.95
$ 2.47 per pill
Buy
Viagra
Sildenafil citrate
130 mg x 60 pills
$ 181.90 $ 171.95
$ 2.87 per pill
Buy
Viagra
Sildenafil citrate
130 mg x 30 pills
$ 103.90 $ 97.95
$ 3.27 per pill
Buy
Viagra
Sildenafil citrate
130 mg x 20 pills
$ 76.90 $ 71.95
$ 3.60 per pill
Buy
Viagra
Sildenafil citrate
130 mg x 10 pills
$ 45.90 $ 42.95
$ 4.29 per pill
Buy

Viagra (Sildenafil citrate) 120 mg

Viagra
Sildenafil citrate
120 mg x 360 pills
$ 571.90 $ 543.95
$ 1.51 per pill
Buy
Viagra
Sildenafil citrate
120 mg x 270 pills
$ 473.90 $ 450.95
$ 1.67 per pill
Buy
Viagra
Sildenafil citrate
120 mg x 180 pills
$ 366.90 $ 348.95
$ 1.94 per pill
Buy
Viagra
Sildenafil citrate
120 mg x 120 pills
$ 269.90 $ 255.95
$ 2.13 per pill
Buy
Viagra
Sildenafil citrate
120 mg x 90 pills
$ 215.90 $ 204.95
$ 2.28 per pill
Buy
Viagra
Sildenafil citrate
120 mg x 60 pills
$ 179.90 $ 170.95
$ 2.85 per pill
Buy
Viagra
Sildenafil citrate
120 mg x 30 pills
$ 99.90 $ 93.95
$ 3.13 per pill
Buy
Viagra
Sildenafil citrate
120 mg x 20 pills
$ 72.90 $ 68.95
$ 3.45 per pill
Buy
Viagra
Sildenafil citrate
120 mg x 10 pills
$ 45.90 $ 42.95
$ 4.29 per pill
Buy

Viagra (Sildenafil citrate) 100 mg

Viagra
Sildenafil citrate
100 mg x 360 pills
$ 427.90 $ 406.95
$ 1.13 per pill
Buy
Viagra
Sildenafil citrate
100 mg x 270 pills
$ 351.90 $ 333.95
$ 1.24 per pill
Buy
Viagra
Sildenafil citrate
100 mg x 180 pills
$ 254.90 $ 241.95
$ 1.34 per pill
Buy
Viagra
Sildenafil citrate
100 mg x 120 pills
$ 174.90 $ 165.95
$ 1.38 per pill
Buy
Viagra
Sildenafil citrate
100 mg x 90 pills
$ 151.90 $ 143.95
$ 1.60 per pill
Buy
Viagra
Sildenafil citrate
100 mg x 60 pills
$ 115.90 $ 109.95
$ 1.83 per pill
Buy
Viagra
Sildenafil citrate
100 mg x 30 pills
$ 67.90 $ 63.95
$ 2.13 per pill
Buy
Viagra
Sildenafil citrate
100 mg x 20 pills
$ 55.90 $ 51.95
$ 2.60 per pill
Buy
Viagra
Sildenafil citrate
100 mg x 10 pills
$ 31.90 $ 29.95
$ 3.00 per pill
Buy

Viagra (Sildenafil citrate) 50 mg

Viagra
Sildenafil citrate
50 mg x 360 pills
$ 395.90 $ 375.95
$ 1.04 per pill
Buy
Viagra
Sildenafil citrate
50 mg x 270 pills
$ 307.90 $ 291.95
$ 1.08 per pill
Buy
Viagra
Sildenafil citrate
50 mg x 180 pills
$ 221.90 $ 210.95
$ 1.17 per pill
Buy
Viagra
Sildenafil citrate
50 mg x 120 pills
$ 160.90 $ 151.95
$ 1.27 per pill
Buy
Viagra
Sildenafil citrate
50 mg x 90 pills
$ 135.90 $ 128.95
$ 1.43 per pill
Buy
Viagra
Sildenafil citrate
50 mg x 60 pills
$ 101.90 $ 95.95
$ 1.60 per pill
Buy
Viagra
Sildenafil citrate
50 mg x 30 pills
$ 60.90 $ 56.95
$ 1.90 per pill
Buy
Viagra
Sildenafil citrate
50 mg x 20 pills
$ 46.90 $ 43.95
$ 2.20 per pill
Buy
Viagra
Sildenafil citrate
50 mg x 10 pills
$ 28.90 $ 26.95
$ 2.69 per pill
Buy

Viagra (Sildenafil citrate) 25 mg

Viagra
Sildenafil citrate
25 mg x 360 pills
$ 289.90 $ 274.95
$ 0.76 per pill
Buy
Viagra
Sildenafil citrate
25 mg x 270 pills
$ 228.90 $ 216.95
$ 0.80 per pill
Buy
Viagra
Sildenafil citrate
25 mg x 180 pills
$ 158.90 $ 150.95
$ 0.84 per pill
Buy
Viagra
Sildenafil citrate
25 mg x 120 pills
$ 118.90 $ 111.95
$ 0.93 per pill
Buy
Viagra
Sildenafil citrate
25 mg x 90 pills
$ 95.90 $ 90.95
$ 1.01 per pill
Buy
Viagra
Sildenafil citrate
25 mg x 60 pills
$ 69.90 $ 65.95
$ 1.10 per pill
Buy
Viagra
Sildenafil citrate
25 mg x 30 pills
$ 41.90 $ 38.95
$ 1.30 per pill
Buy
Viagra
Sildenafil citrate
25 mg x 20 pills
$ 31.90 $ 29.95
$ 1.50 per pill
Buy
Viagra
Sildenafil citrate
25 mg x 10 pills
$ 19.90 $ 17.95
$ 1.79 per pill
Buy

Information

Buy Viagra With Bitcoin Or Credit Card is a potent selective inhibitor of cGMP-specific PDE-5.



Mechanism of action

The implementation of the physiological mechanism of erection is associated with the release of nitric oxide (NO) in the cavernous body during sexual stimulation. This, in turn, leads to an increase in the level of cGMP, the subsequent relaxation of smooth muscle tissue of the cavernous body and an increase in blood flow.

Buy Viagra With Bitcoin Or Credit Card does not have a direct relaxing effect on the isolated cavernous human body, but enhances the effect of nitric oxide by inhibiting PDE-5, which is responsible for the disintegration of cGMP.

Selective Buy Viagra With Bitcoin Or Credit Card against PDE5 in vitro, its activity against PDE5 superior activity against other known PDE isoenzymes: PDE-6 — 10 times; PDE-1 more than 80 times; PDE-2, PDE-4, PDE-7 PDE–11 more than 700 times. Buy Viagra With Bitcoin Or Credit Card is 4000 times more selective for PDE-5 than PDE-3, which is crucial because PDE-3 is one of the key enzymes in the regulation of myocardial contractility.

A prerequisite for the effectiveness of Buy Viagra With Bitcoin Or Credit Card is sexual stimulation.

Buy Viagra With Bitcoin Or Credit Card restores impaired erectile function in conditions of sexual stimulation by increasing blood flow to the cavernous bodies of the penis.

Influence of Buy Viagra With Bitcoin Or Credit Card on other drugs

Buy Viagra With Bitcoin Or Credit Card is a weak inhibitor of cytochrome P450 — 1A2, 2C9, 2C19, 2D6, 2E1 and 3A4 ISOENZYMES (IC50 >150 µmol). When taking Pay For Viagra With Bitcoin in recommended doses, its Cmax is about 1 µmol, so it is unlikely that Buy Viagra With Bitcoin Or Credit Card can affect the clearance of the substrates of these isoenzymes.

Buy Viagra With Bitcoin Or Credit Card increases the hypotensive effect of nitrates both with long-term use of the latter, and with their appointment for urgent indications. In this regard, the use of Pay For Female Viagra With Bitcoin in combination with nitrates or nitric oxide donators is contraindicated. While taking α-adrenoblocker doxazosin (4 and 8 mg) and Buy Sildenafil With Bitcoin (25, 50 and 100 mg) in patients with benign prostate hyperplasia with stable hemodynamics, the average additional decrease in sad/dad in the supine position was 7/7, 9/5 and 8/4 mm Hg.article, respectively, while in the standing position — 6/6, 11/4 mmHg, and 4/5.art. respectively. Reported rare cases of symptomatic postural hypotension in such patients, manifested in the form of dizziness (without fainting). In some sensitive patients receiving α-blockers, simultaneous use of Buy Sildenafil With Bitcoin can lead to symptomatic hypotension.

There were no signs of significant interaction with tolbutamide (250 mg) or warfarin (40 mg), which are metabolized by CYP2C9 isoenzyme.

Pay For Female Viagra With Bitcoin (100 mg) has no effect on the pharmacokinetics of the HIV protease inhibitor, saquinavir, which is a substrate of CYP3A4 isoenzyme, at its constant level in the blood.

The simultaneous use of Buy Viagra With Bitcoin Or Credit Card at equilibrium (80 mg 3 times a day) leads to an increase in the AUC and Cmax of bosentan (125 mg 2 times a day) by 49.8 and 42%, respectively.

Buy Viagra With Bitcoin Or Credit Card (50 mg) does not cause an additional increase in bleeding time when taking acetylsalicylic acid (150 mg).

Buy Viagra With Bitcoin Or Credit Card (50 mg) does not increase the hypotensive effect of alcohol in healthy volunteers with Cmax of alcohol in the blood on average 0.08‰ (80 mg/DL).

In patients with hypertension, no signs of interaction of Pay For Female Viagra With Bitcoin (100 mg) with amlodipine were found. The average additional reduction in blood PRESSURE in the supine position is 8 mm Hg.V. (systolic) and 7 mm Hg.V. (diastolic).

The use of Buy Viagra With Bitcoins in combination with antihypertensive agents does not lead to additional side effects.

Clinical data

Cardiac studies. The use of Buy Viagra With Bitcoin Or Credit Card in doses up to 100 mg did not lead to clinically significant ECG changes in healthy volunteers. The maximum decrease in systolic pressure in the supine position after taking Buy Viagra With Bitcoin Or Credit Card at a dose of 100 mg was 8.3 mm Hg.art., and diastolic pressure — 5.3 mm Hg.a More pronounced, but also transient effect on blood PRESSURE was observed in patients taking nitrates (see "Contraindications" and "Interaction").

In a study of the hemodynamic effect of Buy Viagra With Bitcoin Or Credit Card in a single dose of 100 mg in 14 patients with severe coronary artery disease (more than 70% of patients had stenosis of at least one coronary artery), systolic and diastolic resting pressure decreased by 7 and 6%, respectively, and pulmonary systolic pressure decreased by 9%. Buy Viagra With Bitcoin Or Credit Card did not affect cardiac output and did not interfere with blood flow in stenotic coronary arteries, and also led to an increase (by about 13%) of adenosine-induced coronary flow in both stenotic and intact coronary arteries. In a double-blind placebo-controlled study of 144 patients with erectile dysfunction and stable angina, taking antianginal drugs (except nitrates), exercise was performed until the severity of symptoms of angina increased. The duration of the exercise was significantly longer (19.9 seconds; 0.9–38.9 seconds) in patients taking Buy Viagra With Bitcoin Or Credit Card in a single dose of 100 mg, compared with patients receiving placebo.

In a randomized double-blind placebo-controlled study, the effect of changing the dose of Buy Viagra With Bitcoin Or Credit Card (up to 100 mg) in men (n=568) with erectile dysfunction and hypertension, taking more than two antihypertensive drugs, was studied. Buy Viagra With Bitcoins improved erection in 71% of men compared to 18% in the placebo group. The frequency of adverse effects was comparable to that in other groups of patients, as well as in those taking more than three antihypertensive drugs.

Studies of visual impairment. In some patients, 1 h after taking Buy Viagra With Bitcoin Or Credit Card at a dose of 100 mg with the Farnsworth-Mansell test 100 revealed a slight and transient violation of the ability to distinguish shades of color (blue/green). After 2 hours after taking the drug, these changes were absent. It is believed that color vision impairment is caused by inhibition of PDE-6, which is involved in the process of color transmission in the retina. Buy Viagra With Bitcoins had no effect on visual acuity, contrast perception, electroretinogram, IOP or pupil diameter.

Cardiovascular complications

During the post-marketing use of Buy Kamagra With Bitcoin for the treatment of erectile dysfunction, adverse events such as severe cardiovascular complications (including myocardial infarction, unstable angina, sudden cardiac death, ventricular arrhythmia, hemorrhagic stroke, transient ischemic attack, hypertension and hypotension) were reported, which had a temporary connection with the use of Buy Viagra With Bitcoin Or Credit Card. Most of these patients, but not all of them, had risk factors for cardiovascular complications. Many of these adverse events were observed shortly after sexual activity, and some were observed after taking Buy Viagra Online Bitcoin Or Credit Card without subsequent sexual activity. It is not possible to establish a direct link between the reported adverse events and those or other factors.

Visual impairment

In rare cases, during post-approval use of all of the inhibitors of PDE5, including Pay For Female Viagra With Bitcoin, reported NESN is a rare disease and the cause of the decrease or loss of vision. Most of these patients had risk factors, such as decreased ratios of excavation diameter to optic disc (stagnant disc), age over 50, diabetes, hypertension, CHD, hyperlipidemia, and Smoking. In an observational study evaluated whether recent use of drugs class of inhibitors PDE-5 with an acute onset NESN. The results indicate approximately a 2-fold increase in risk of developing NESN within 5T1/2 after application of the PDE-5 inhibitor. According to published literature, the annual incidence of npins IS 2.5–11.8 cases per 100,000 men aged ≥50 years in the General population. Patients should be advised to stop Buy Viagra With Bitcoin Or Credit Card therapy in case of sudden loss of vision and consult a doctor immediately. Persons who have already had a case NESN have an increased risk of relapse NESN. Therefore, the doctor should discuss this risk with such patients, as well as the potential chance of adverse effects of PDE-5 inhibitors. PDE-5 inhibitors, including Buy Viagra With Bitcoin Or Credit Card, in such patients should be used with caution and only in situations where the expected benefit outweighs the risk.

When using the drug Buy Viagra With Bitcoin Or Credit Card in doses exceeding the recommended, adverse events were similar to those noted above, but usually more common.

*Side effects identified during post-marketing studies.

Interaction

Effect of other drugs on the pharmacokinetics of Buy Viagra With Bitcoin Or Credit Card

The metabolism of Buy Viagra With Bitcoin Or Credit Card occurs mainly under the action of CYP3A4 isoenzyme (main pathway), so inhibitors of this isoenzyme can reduce the clearance of Buy Viagra With Bitcoin, and inducers, respectively, increase the clearance of Buy Female Viagra With Bitcoin. A decrease in the clearance of Buy Viagra With Bitcoin Or Credit Card with simultaneous use of inhibitors of CYP3A4 isoenzyme (ketoconazole, erythromycin, cimetidine).

Cimetidine (800 mg), a nonspecific inhibitor of CYP3A4 isoenzyme, when taken together with Buy Sildenafil With Bitcoins (50 mg) causes an increase in the concentration of Buy Viagra With Bitcoin Or Credit Card in plasma by 56%.

A single dose of 100 mg of Buy Kamagra With Bitcoin together with erythromycin (500 mg/day 2 times a day for 5 days), a moderate inhibitor of CYP3A4 isoenzyme, while achieving a constant concentration of erythromycin in the blood, leads to an increase in the AUC of Buy Viagra With Bitcoin Or Credit Card by 182%.

When co-administered Buy Female Viagra With Bitcoins (once 100 mg) and saquinavir (1200 mg/day 3 times daily), an inhibitor of HIV protease and of CYP3A4, on the background to achieve a constant concentration of saquinavir in the blood, Cmax of Buy Viagra With Bitcoin Or Credit Card was increased by 140% and the AUC increased by 210%.

Stronger inhibitors of CYP3A4 isoenzyme, such as ketoconazole and Itraconazole, can cause more pronounced changes in the pharmacokinetics of Buy Viagra With Bitcoin Or Credit Card.

The simultaneous use of Buy Viagra With Bitcoin Or Credit Card (100 mg once) and ritonavir (500 mg 2 times a day), an inhibitor of HIV protease and a strong inhibitor of cytochrome P450, on the background to achieve a constant concentration of ritonavir in the blood leads to an increase in Cmax of Buy Viagra With Bitcoin Or Credit Card by 300% (4 times), a AUC by 1000% (11-fold). After 24 h, the concentration of Buy Viagra With Bitcoin Or Credit Card in blood plasma is about 200 ng/ml (after a single application of one Buy Kamagra With Bitcoins — 5 ng/ml). This is consistent with the ritonavir effect on a wide range of cytochrome P450 substrates. Buy Female Viagra With Bitcoin does not affect the pharmacokinetics of ritonavir. Given these data, the simultaneous reception of ritonavir and Buy Viagra With Bitcoin Or Credit Card is not recommended. In any case, the maximum dose of Kamagra Bitcoin Pharmacy Online under any circumstances should not exceed 25 mg for 48 hours. If Buy Viagra With Bitcoin Or Credit Card is taken in the recommended doses, patients receiving strong inhibitors of CYP3A4 isoenzyme at the same time, then Cmax free Buy Sildenafil With Bitcoin Or Credit Card does not exceed 200 nm, and the drug is well tolerated.

Single administration of antacid (magnesium hydroxide/aluminum hydroxide) does not affect the bioavailability of Female Viagra Bitcoin Pharmacy Online.

Studies involving healthy volunteers with simultaneous use of endothelin receptor antagonist, bosentan (CYP3A4 isoenzyme inducer (moderate), CYP2C9, and possibly CYP2C19) in Css (125 mg 2 times a day) and How To Buy Viagra With Bitcoin Online Pharmacy in Css (80 mg 3 times a day) showed a decrease in AUC and Cmax Buy Viagra With Bitcoin Or Credit Card by 62.6 and 52.4%, respectively. Buy Kamagra With Bitcoin increased the AUC and Cmax of bosentan by 49.8 and 42%, respectively.

It is assumed that the simultaneous use of Buy Viagra With Bitcoin Or Credit Card with powerful inducers of CYP3A4 isoenzyme, such as rifampicin, can lead to a greater decrease in the concentration of Buy Kamagra Bitcoin in blood plasma.

CYP2D6 isoenzyme inhibitors (SSRIs, tricyclic antidepressants), thiazide and thiazide-like diuretics, ACE inhibitors and calcium antagonists have no effect on the pharmacokinetics of Buy Viagra With Bitcoin Or Credit Card.

Azithromycin (500 mg/day for 3 days) has no effect on AUC, Cmax, Tmax, excretion rate constant and T1/2 Buy Viagra With Bitcoin Or Credit Card or its main circulating metabolite.

Pay For Female Viagra With Bitcoin

Our bestsellers